2007
CURE Award, Funded by the Rhode Island Award
Intranasal Delivery Of Sustained-Release Anticonvulsant Neuropeptide Nanoparticles In Seizure Therapy
Michael J. Kubek, PhD
Indiana University School of Medicine, Indianapolis, IN
A new class of brain-derived compounds known as anticonvulsant neuropeptides has emerged after years of basic and clinical research. Unfortunately, delivering such neuropeptides to treat epilepsy has been difficult because of their inability to access the brain. The goal of this Dr. Kubek’s research is to develop a neuropeptide-containing nanoparticle nasal spray for seizure therapy. The hope is that this research will lead to a new treatment for seizure prevention and ultimately a cure for seizure disorders.