Epilepsy can often be detected early by recording brain electrical activity with EEG, a technique that reveals abnormal rhythms when the disease is present. This project focuses on high frequency oscillations (HFOs) which are brief and ultrafast electrical events observed on EEGs. HFOs are emerging as promising biomarkers of epilepsy. While HFOs have been linked to epilepsy, no method currently exists to specifically disrupt HFOs and determine whether this reduces seizures. Dr. Lisgaras and his team will test whether precise control of HFOs can provide powerful new therapeutic options. If successful, this work could pave the way for innovative treatments that improve seizure control and transform epilepsy care.
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