Detailed Description: Generally, benign epilepsy with centro-temporal spikes is characterized by infrequent focal sensorimotor seizures in the face during sleep, which may secondarily generalize, along with spike-wave discharges, reflecting nonlesional cortical excitability from rolandic regions.
The high comorbid prevalence of attention deficit hyperactivity disorder and epilepsy suggests that there is a bidirectional relationship between these disorders. Cognitive impairment and attention problems are particularly crucial issues in children with epilepsy who are in a vigorous phase of neurodevelopment.
Primary Outcome Measures: 1. To compare between the effect of oral steroids and diazepam regarding normalization of sleep EEG, 2. To compare between the effect of oral steroids and diazepam regarding improvement of cognitive functions of patients with benign childhood epilepsy with centrotemporal spikes.
Anticipated Study Start Date: April 20, 2018
Estimated Study Completion Date: January 15, 2020
Ages Eligible for Study: up to 16 Years (Child)
Sexes Eligible for Study: All
Accepts Healthy Volunteers: Yes
- History and EEG findings of benign epilepsy with centrotemporal spikes
- Genetic disorders
- Metabolic or neurodegenerative disease
- Gross motor delay