Research Grants Awarded

CURE Epilepsy sees research as the key to finding cures for the epilepsies. Each year, CURE Epilepsy funds investigator-initiated grants supporting promising trends in the field and the potential for breakthroughs in a specified area.

Learn About Our Research Initiatives

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Preventing Epileptogenesis Through RBM3-Inducing ASOs: A Novel Approach to Neuroprotection, Antiinflammation, and Seizure Control

Sonja Broer, PhD, Florian Heyd, PhD, Rosella Di Sapia, PhD

The ASO developed by this team activates a “cold shock” protein named RBM3 that protects brain cells—without needing to cool the body.

Targeting Dentate Gyrus CCK INs to Limit Seizure Burden and Behavioral Impairments in Epilepsy

Mahboubeh Ahmadi, PhD

This project will study how epilepsy changes the way CCK interneurons work and whether fixing their activity can reduce seizures and improve memory, motivation, and behavior.

Determining Pathological Immature Astroglia Mechanisms in Drug Resistant Epilepsy Patients

Aswathy AmmothumKandy, PhD

In this project, she and her team will study why these cells stay in a disease state in epilepsy and look for ways to help them return to normal.

Fine-Tuning the 3’UTR as a Novel Therapeutic Strategy for Genetic Developmental and Epileptic Encephalopathies

Alex Felix, PhD

The goal of this project is to develop a novel Antisense Oligonucleotide (ASO) strategy to treat DEE syndromes by changing how certain genes are processed within the cell.

High Frequency Oscillations (HFO) as a Therapeutic Target in Temporal Lobe Epilepsy (TLE)

Christos Lisgaras, PhD

Dr. Lisgaras and his team will test whether precise control of HFOs can provide powerful new therapeutic options. If successful, this work could pave the way for innovative treatments that improve seizure control and transform epilepsy care.