Mechanisms
Advances in high throughput metagenomic sequencing, a powerful technology that allows researchers to sequence DNA and RNA rapidly, have increasingly highlighted the role of gut microbiota imbalance in epilepsy.
Mechanisms
New research has shown that the process of insulin resistance in the brain affects both Alzheimer's disease and epilepsy and may be a linking factor between the two diseases.
Genetics, Rare Epilepsies
Scientists at St. Jude Children’s Research Hospital developed a cortical organoid model for UBA5-associated encephalopathy, revealing a new way to possibly address developmental defects.
Dravet Syndrome, Treatment
A potential new gene therapy for Dravet syndrome increases survival and prevents seizures, according to initial tests in mice.
Mechanisms, Treatment Resistant/Refractory
In a large cohort of children with drug-resistant epilepsy, researchers showed that "fast ripples" are the best biomarkers to predict surgical outcomes, but they can be seen in only 43% of patients.
Genetics, Treatment Resistant/Refractory
Certain common genetic changes might make some people with focal epilepsy less responsive to seizure medications, according to a recent study conducted by CURE Epilepsy grantee Professor Sanjay Sisodiya of UCL Queen Square Institute of Neurology.
